The symbiotic microorganisms in the gut of termites play a key role in the digestion of cellulose and nitrogen metabolism. Therefore, disruption of these symbioses activity can open a door toward termite management. Thus, the current study aimed to exploit termite gut bacterial capacity in order to utilize it for efficient termite control. So, in the current study, gut bacteria of Microcerotermes diversus have been extracted, cultivated on both liquid and solid media, and screened with a range of antibiotics to find the most effective antibiotics. Results showed that chloramphenicol and nalidixic acid were the most effective antibiotics in preventing the colony unit formation of the gut bacteria amongst 16 antibiotics tested. Also, from two chitin synthesis inhibitors tested hexaflumuron with an LC₅₀ of 613.9 µg ml⁻¹ was more toxic than lufenuron with an LC₅₀ of 1414.5 µg ml⁻¹. Thus, two antibiotics (chloramphenicol and nalidixic acid) were used simultaneously with a sub-lethal concentration of hexaflumuron against the termite and a variety of factors such as wood consumption rate, running speed, body water content, and tunneling activity were evaluated under laboratory conditions. Results showed that the combination of these two antibiotics (chloramphenicol and nalidixic acid) with hexaflumuron caused a significant decrease in termite consumption rate, running speed, and tunneling behavior, but didn’t affect the body water contents of termites. These results suggest that using a combination of antibiotic/s and hexaflumuron is a promising management practice to get a suitable control measure for the studied termite.

白蚁肠道中的共生微生物在纤维素和氮代谢的消化中起关键作用。因此，这些共生酶活性的破坏可以为白蚁管理打开一扇门。因此，当前的研究旨在开发白蚁肠道细菌的能力，以便将其用于有效的白蚁控制。因此，在当前的研究中，已提取了微拟白蚁的肠道细菌，在液体和固体培养基上进行了培养，并用一系列抗生素进行了筛选，以找到最有效的抗生素。结果显示，在所测试的16种抗生素中，氯霉素和萘啶酸是预防肠道细菌菌落单位形成最有效的抗生素。另外，由两种甲壳质合成抑制剂通过LC检验了六氟磺隆₅₀的613.9微克毫升^-1比虱螨脲的毒性与LC ₅₀的1414.5微克毫升^-1。因此，同时使用两种抗生素（氯霉素和萘啶酸）以及针对白蚁的亚致死浓度的六氟磺隆，并在实验室条件下评估了各种因素，例如木材消耗率，运行速度，人体含水量和挖掘活性。 。结果表明，这两种抗生素（氯霉素和萘啶酸）与六氟磺隆联合使用可显着降低白蚁的消耗速度，运行速度和隧穿行为，但不会影响白蚁的体内水分。这些结果表明，结合使用抗生素和六氟尿嘧啶是一种有前途的管理实践，可为所研究的白蚁获得合适的控制措施。