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Preparation and antibacterial properties of gold nanoparticles: a review
Environmental Chemistry Letters ( IF 15.7 ) Pub Date : 2020-08-12 , DOI: 10.1007/s10311-020-01071-0
Xiao Gu , Zhixiang Xu , Lipeng Gu , Huayu Xu , Fengxia Han , Bo Chen , Xuejun Pan

The overuse of antibiotics has led to an increase in bacterial resistance and, in turn, to a decreasing efficiency of the rare available antibiotics. Alternatively, gold nanoparticles are promising antibacterials due to their high specific surface area, easy modification by functional groups and broad-spectrum antibacterial activity. Their antibacterial properties are closely related to particle size, dispersibility and surface modification, which can be tuned by adjusting reaction conditions. Here, we review the synthesis and antibacterial performance of gold nanoparticles in the raw form or modified with metal, organic compounds and carbon. We present the effect of reaction conditions on particle dispersibility and size. We compare the various synthesis methods. Antibacterial activities and their mechanisms are discussed.



中文翻译:

金纳米粒子的制备及其抗菌性能研究进展

抗生素的过度使用导致细菌耐药性增加,进而导致稀有抗生素的效率下降。或者,金纳米颗粒由于其高的比表面积,易于被官能团修饰和广谱抗菌活性而成为很有前途的抗菌剂。它们的抗菌性能与粒径,分散性和表面改性密切相关,可以通过调节反应条件进行调节。在这里,我们审查了原始形式或经金属,有机化合物和碳改性的金纳米颗粒的合成和抗菌性能。我们介绍了反应条件对颗粒分散性和尺寸的影响。我们比较了各种合成方法。讨论了抗菌活性及其机理。

更新日期:2020-08-12
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