In recent years, the interest in biologically active compounds of natural origin has increased significantly. Researchers' research focuses on increasing the activity of curcumin by forming complexes with metals such as vanadium, iron, copper or gallium. Introduction of metal compounds to curcumin increases the scope of application in pharmacology. The main direction of research development is the treatment of tumors, among others stomach cancer or leukemia. Curcuminoids are the main components of turmeric (Curcuma longa L.), a plant from India and South-East Asia. Due to its intense yellow-orange color and pleasant aroma, the powdered rootstalk is widely used in the food industry, as natural dye and spice. The chemical compound responsible for the characteristic color of rhizomes of curcuma is 1,6-heptadien-3,5-dione-1,7-bis(4-hydroxy-3-methoxyphenyl) - (1E, 6E) called curcumin. This work aims to characterize curcumin in terms of its structure, therapeutic properties and also as a substrate for the synthesis of valuable derivatives like tetrahydrocurcumin. Knowledge about this relationship based on literature analysis will enable a better understanding of the factors responsible for its biological activity.

近年来，人们对天然来源的生物活性化合物的兴趣大大增加。研究人员的研究重点是通过与钒，铁，铜或镓等金属形成络合物来提高姜黄素的活性。将金属化合物引入姜黄素增加了药理学的应用范围。研究发展的主要方向是肿瘤的治疗，尤其是胃癌或白血病。姜黄素是姜黄（Curcuma longa L.）的主要成分，姜黄是印度和东南亚的植物。由于其强烈的橙黄颜色和宜人的香气，粉状的根茎被广泛用作食品工业中的天然染料和香料。引起姜黄根状茎特征颜色的化合物为1,6-庚二烯-3,5-二酮-1，7-双（4-羟基-3-甲氧基苯基）-（1E，6E）称为姜黄素。这项工作旨在根据其结构，治疗特性来表征姜黄素，并作为合成有价值的衍生物（如四氢姜黄素）的底物。基于文献分析的关于这种关系的知识将使人们能够更好地理解造成其生物学活性的因素。