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Synthesis, structure and evaluation of anticancer activity of 4-amino-1,3-thiazolinone/pyrazoline hybrids
Journal of Molecular Structure ( IF 3.8 ) Pub Date : 2021-01-01 , DOI: 10.1016/j.molstruc.2020.129059
Andrii Pyrih , Mariusz Jaskolski , Andrzej K. Gzella , Roman Lesyk

Abstract A synthetic approach towards 4-arylamino-5-(2-pyrazoline-1-yl)-methylidene-1,3-thiazoline-2-ones with good yields is described. IR and NMR spectral characterization as well as full X-ray crystal structure analysis of the prepared compounds is described. Also, for the presented compounds their anticancer profiles were tested.

中文翻译:

4-氨基-1,3-噻唑啉酮/吡唑啉杂化物的合成、结构和抗癌活性评价

摘要 描述了一种具有良好收率的 4-芳基氨基-5-(2-pyrazoline-1-yl)-methylidene-1,3-thiazoline-2-ones 的合成方法。描述了制备的化合物的 IR 和 NMR 光谱表征以及全 X 射线晶体结构分析。此外,对于所呈现的化合物,测试了它们的抗癌特性。
更新日期:2021-01-01
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