An efficient NIS-promoted two-step radical addition of thiols to allenamides was developed to create a workable route to 1,3-dithioethers. The reaction exhibited good functional group tolerance and high efficiency, affording the products in good to excellent yields. Moreover, cyclic dithioethers could be obtained by using 1,2-dithiols as substrates. Mechanistic investigations including calculation study indicated that a two-step radical process is likely involved in this transformation.

中文翻译：

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NIS通过两步自由基过程促进烯丙酰胺的分子间双亚磺基化：合成1,3-二硫醚

已开发出一种有效的NIS促进的将硫醇两步自由基加成到烯丙基酰胺上的方法，以创建通往1,3-二硫醚的可行途径。该反应显示出良好的官能团耐受性和高效率，从而提供了良好至优异产率的产物。此外，通过使用1，2-二硫醇作为底物可以获得环状二硫醚。包括计算研究在内的机械研究表明，这一转变可能涉及两步根本过程。