Essential oils and antimicrobial peptides are two well-known safe and natural products that have been considered as alternatives to antibiotics. In the present study, the antibacterial activity of four plant essential oils and one lactoferrin-derived peptide was investigated. The chemical profile of each essential oil was determined by GC and GC–MS. Antimicrobial activity was shown against seven clinically isolated veterinary pathogens. MIC and MBC assessment of the essential oils and cLFchimera exhibited different antibacterial properties (MIC from a range of 62.5 to 500 µg/mL and 3.5 to 39.0 µg/mL for essential oils and cLFchimera, respectively). Compared to the essential oils, cLFchimera showed more significant antibacterial activity. Among the essential oils, Vitex agnus-castus and Salvia officinalis showed relatively better antibacterial activity. The in vitro results reported here suggested that, for animals suffering from these pathogens, cLFchimera and the essential oils particularly Vitex agnus-castus could be considered as potential antimicrobial agents.

中文翻译：

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某些植物精油和抗菌肽对某些临床分离的病原体的抗菌活性

香精油和抗菌肽是两种众所周知的安全天然产物，被认为可以替代抗生素。在本研究中，研究了四种植物精油和一种乳铁蛋白衍生肽的抗菌活性。每种精油的化学特征通过GC和GC-MS确定。已显示出对7种临床分离的兽医病原体的抗菌活性。精油和cLFchimera的MIC和MBC评估显示出不同的抗菌性能（精油和cLFchimera的MIC分别为62.5至500 µg / mL和3.5至39.0 µg / mL。）与精油相比，cLFchimera具有更显着的抗菌活性。在精油中，牡荆-山茱off和丹参具有相对较好的抗菌活性。此处报道的体外结果表明，对于患有这些病原体的动物，CLFchimera和精油，尤其是荆芥（Vitex agnus-castus）可被视为潜在的抗菌剂。