We aim to determine the prevalence of HIV nonsuppression and factors associated with it. This is a cross-sectional multicenter study carried out in January 2016 with data of the VACH Cohort, a registry participated by 23 hospitals from most regions of Spain. The prevalence of HIV nonsuppression, defined as HIV RNA ≥200 copies/mL, is documented. The possible association of HIV nonsuppression with sociodemographic and clinical variables is assessed with a logistic regression analysis. A total of 30,843 adult patients are included; 7,358 of them (23.86%) have nonsuppressed HIV. An association is found between nonsuppression of HIV and the following variables: lower body mass index, lower age of patients in their last registered visit, lower number of visits carried out during follow-up, lower last available CD4 cell count, higher age of patients at the time of their HIV infection diagnosis, higher lowest available CD4 cell count, higher highest available HIV RNA, enrolment in the Cohort in first years of the HIV epidemic, region of Spain where the patient is attended other than Andalusia, HIV risk factor other than sexual, occurrence of death during follow-up, hepatitis C coinfection, being a smoker, pertaining to groups A1 or A2 of the CDC groups classification, and not taking antiretroviral treatment, p < .001 in all cases. HIV nonsuppression is still common with the effective antiretroviral treatment nowadays available. HIV nonsuppression is associated with HIV risk factor other than sexual, hepatitis C coinfection, and being a smoker, among other factors.

中文翻译：

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西班牙 VACH 队列中与不抑制 HIV 感染相关的因素。

我们的目标是确定 HIV 非抑制的流行率以及与之相关的因素。这是一项横断面多中心研究，于 2016 年 1 月使用 VACH 队列的数据进行，该队列由来自西班牙大部分地区的 23 家医院参与。记录了 HIV 未抑制的流行率，定义为 HIV RNA ≥200 拷贝/mL。使用逻辑回归分析评估 HIV 未抑制与社会人口学和临床变量之间可能的关联。共纳入 30,843 名成年患者；其中 7,358 人 (23.86%) 患有未抑制的 HIV。发现不抑制 HIV 与以下变量之间存在关联：较低的体重指数、上次登记访问时患者的年龄较低、随访期间进行的访问次数较少、上次可用的 CD4 细胞计数较低、 在所有情况下p < .001。在当今可用的有效抗逆转录病毒治疗中，HIV 不受抑制仍然很常见。HIV 未抑制与性、丙型肝炎合并感染和吸烟等因素以外的 HIV 风险因素有关。