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Goal-directed actions transiently depend on dorsal hippocampus.
Nature Neuroscience ( IF 25.0 ) Pub Date : 2020-08-10 , DOI: 10.1038/s41593-020-0693-8
Laura A Bradfield 1, 2 , Beatrice K Leung 3 , Susan Boldt 4 , Sophia Liang 3 , Bernard W Balleine 3
Affiliation  

The role of the hippocampus in goal-directed action is currently unclear; studies investigating this issue have produced contradictory results. Here we reconcile these contradictions by demonstrating that, in rats, goal-directed action relies on the dorsal hippocampus, but only transiently, immediately after initial acquisition. Furthermore, we found that goal-directed action also depends transiently on physical context, suggesting a psychological basis for the hippocampal regulation of goal-directed action control.



中文翻译:

目标导向的动作暂时取决于背侧海马。

目前尚不清楚海马在定向运动中的作用。研究此问题的研究产生了矛盾的结果。在这里,我们通过证明在大鼠中,目标定向动作依赖于背侧海马,但只是在最初获得后立即进行,来调和这些矛盾。此外,我们发现目标导向的动作也暂时取决于身体情况,这为目标导向动作控制的海马调节提供了心理基础。

更新日期:2020-08-10
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