Dense multicilia in protozoa and metazoa generate a strong force important for locomotion and extracellular fluid flow. During ciliogenesis, multiciliated cells produce hundreds of centrioles to serve as basal bodies through various pathways including deuterosome‐dependent (DD), hyper‐activated mother centriole‐dependent (MCD) and basal bodydependent (BBD) pathways. The centrosome‐free planarian Schmidtea mediterranea is widely used for regeneration studies because its neoblasts are capable of regenerating any body part after injury. However, it is currently unclear how the flatworms generate massive centrioles for multiciliated cells in the pharynx and body epidermis when their cells are initially centriole‐free.

中文翻译：

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涡虫增殖过程中中心粒生物发生的特征

原生动物和后生动物中密集的多纤毛产生强大的力量，对运动和细胞外液流动很重要。在纤毛发生过程中，多纤毛细胞通过多种途径产生数百个中心粒作为基体，包括氘体依赖性（DD）、高激活母体中心粒依赖性（MCD）和基底体依赖性（BBD）途径。无中心体涡虫 Schmidtea mediterranea 被广泛用于再生研究，因为其新生细胞能够在受伤后再生任何身体部位。然而，目前尚不清楚扁虫如何在它们的细胞最初无中心粒时为咽部和身体表皮中的多纤毛细胞产生大量中心粒。