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Polyreactive Antibodies Bridge Immunity Particles to Pathogen.
Trends in Parasitology ( IF 9.6 ) Pub Date : 2020-08-10 , DOI: 10.1016/j.pt.2020.07.012
Henrique Machado 1 , Luisa M Figueiredo 1
Affiliation  

Humans are protected from most African trypanosomes via high-density lipoproteins, known as trypanosome lytic factor (TLF). In humans, IgM antibodies are found associated with TLF. The recent work by Verdi et al. studied the origin of these antibodies and their binding partners, suggesting a new model for TLF uptake.



中文翻译:

多反应性抗体将免疫颗粒桥接至病原体。

人类通过高密度脂蛋白(称为锥虫溶解因子(TLF))免受大多数非洲锥虫的侵害。在人类中,发现IgM抗体与TLF相关。Verdi等人最近的工作。研究了这些抗体及其结合伴侣的来源,为TLF摄取提供了一种新模型。

更新日期:2020-09-23
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