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Modeling Potential Autophagy Pathways in COVID-19 and Sarcoidosis.
Trends in Immunology ( IF 16.8 ) Pub Date : 2020-08-10 , DOI: 10.1016/j.it.2020.08.001
Alain Calender 1 , Dominique Israel-Biet 2 , Dominique Valeyre 3 , Yves Pacheco 1
Affiliation  

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and mainly affects the lungs. Sarcoidosis is an autoinflammatory disease characterized by the diffusion of granulomas in the lungs and other organs. Here, we discuss how the two diseases might involve some common mechanistic cellular pathways around the regulation of autophagy.



中文翻译:

在COVID-19和结节病中模拟潜在的自噬途径。

冠状病毒病2019(COVID-19)由严重的急性呼吸系统综合症冠状病毒2(SARS-CoV-2)引起,主要影响肺部。结节病是一种自身炎症性疾病,其特征是肉芽肿在肺和其他器官中扩散。在这里,我们讨论两种疾病可能如何涉及自噬调节周围的一些常见的机械性细胞途径。

更新日期:2020-09-24
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