Based on a broad public database compilation, we support the hypothesis that germinal polymorphisms may regulate the expression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cellular target itself and proteases controlling the process of its shedding or, conversely, its internalization. Consequently, a genetic influence on individual susceptibility to coronavirus disease 2019 (COVID-19) infection is strongly suspected.

中文翻译：

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宿主多态性可能会影响SARS-CoV-2的传染性。

基于广泛的公共数据库汇编，我们支持以下假设：生发多态性可能会调节严重急性呼吸综合征冠状病毒2（SARS-CoV-2）细胞靶标本身的表达以及控制其脱落过程的蛋白酶，或者相反，蛋白酶会控制其脱落过程内部化。因此，强烈怀疑对个人对冠状病毒病2019（COVID-19）感染的易感性有遗传影响。