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Eco-friendly biosurfactant from Wickerhamomyces anomalus CCMA 0358 as larvicidal and antimicrobial.
Microbiological Research ( IF 6.7 ) Pub Date : 2020-08-09 , DOI: 10.1016/j.micres.2020.126571
Natalia de Andrade Teixeira Fernandes 1 , Angélica Cristina de Souza 1 , Luara Aparecida Simões 1 , Gustavo Magno Ferreira Dos Reis 1 , Karla Teixeira Souza 1 , Rosane Freitas Schwan 1 , Disney Ribeiro Dias 2
Affiliation  

Kitchen waste oil (KWO) was evaluated as a substrate for production of biosurfactant by Wickerhamomyces anomalus CCMA 0358 and was tested against Aedes aegypti larvae, the mosquito causing neglected diseases, such as dengue fever, Zika, and Chikungunya, achieving 100 % mortality in the lowest concentration (6.25 %) evaluated in 24 h. Furthermore, possible applications of this compound were evaluated as antibacterial, antiadhesive, and antifungal. At a concentration of 50 %, the biosurfactant was found to inhibit the growth of Bacillus cereus, showing high inhibitions levels against Salmonella Enteritidis, Staphylococcus aureus, and Escherichia coli. The antifungal activity was evaluated against Aspergillus, Cercospora, Colletotrichum, and Fusarium, obtaining results of up to 95 % inhibition. In addition to these promising results, the yeast W. anomalus produced the biosurfactant from an inexpensive substrate, which increases the possibility of its application in several industries owing to the low cost involved.



中文翻译:

来自Wickerhamomyces anomalus CCMA 0358的生态友好型生物表面活性剂,作为杀幼虫剂和抗菌剂。

厨房废油(KWO)被Wickerhamomyces anomalus CCMA 0358评估为生产生物表面活性剂的底物,并经过了埃及伊蚊幼虫的测试,该伊蚊幼虫是被忽略的疾病,例如登革热,寨卡病毒和基孔肯雅病,死亡率达到100%在24小时内评估出最低浓度(6.25%)。此外,将该化合物的可能应用评估为抗菌,抗粘着和抗真菌。浓度为50%时,发现该生物表面活性剂可抑制蜡状芽孢杆菌的生长,对肠炎沙门氏菌,金黄色葡萄球菌大肠杆菌具有较高的抑制水平。。评估了抗曲霉菌,鹿角孢菌,炭疽菌镰刀菌的抗真菌活性,获得了高达95%的抑制效果。除了这些令人鼓舞的结果,酵母W. anomalus还从廉价的底物中生产出了生物表面活性剂,由于涉及的成本较低,因此增加了其在多种行业中应用的可能性。

更新日期:2020-08-09
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