Microalgae are primary producers in aquatic environments, and their growth is often accompanied and affected by bacteria. Although there are some studies about the relationship between microalgae and bacteria, few studies focused on bait-microalgae. Based on 16S rDNA amplicon sequencing, bacterial community structure and composition associated with seven common bait-microalgae, including Isochrysis galbana 3009, I. galbana 3010, I. galbana 3011, Thalassiosira pseudonana 9005, T. pseudonana 9006, Nannochloropsis oceanica 0001 and N. oceanica 0141, were comprehensively analyzed. Our results indicated that bacteria affiliated with phylum Alphaproteobacteria and Gammaproteobacteria and genera Marinobacter, Oceanicaulis and Dinoroseobacter dominated in all these seven bait-microalgae. Based on alpha and beta diversity analysis, we were interested to found that there were significant differences in the bacterial community between different microalgal species, while the differences were relatively small among the same species. When further searching for putative effect of dominant bacteria on the growth of microalgae, we found that the growth of all these seven microalgae was all improved significantly during co-cultivation with Marinobacter sp. When I. galbana 3011 was co-cultured with other three dominant bacteria, including Algoriphagus sp., Dinoroseobacter sp., and Oceanicaulis sp., the growth was improved significantly to different degrees. Taken together, the present work fully characterized the bacterial community associated with seven bait-microalgae and had a tentative exploration of algae-bacteria interaction, which will help improve the yield and quality of bait-microalgae during their cultivation processes.

微藻是水生环境中的主要生产者，它们的生长通常伴随并受细菌影响。尽管有一些关于微藻与细菌之间关系的研究，但很少有研究关注诱饵微藻。基于16S rDNA扩增子测序，与7种常见诱饵微藻相关的细菌群落结构和组成，包括等鞭金藻3009，加尔巴纳I. galbana 3010，加尔各答I. galbana 3011，Thalassiosira pseudonana 9005，T. pseudonana 9006，Nannochloropsis oceanica 0001和N.对Oceanica 0141进行了全面分析。我们的结果表明细菌与门相关α-变形菌和γ-变形菌和属Marinobacter，Oceanicaulis和Dinoroseobacter在所有这七个饵料微藻为主。基于α和β多样性分析，我们有兴趣发现不同微藻物种之间的细菌群落存在显着差异，而同一物种之间的差异相对较小。在进一步寻找优势细菌对微藻生长的推定作用时，我们发现与Marinobacter sp。共培养期间，所有这七个微藻的生长均得到了显着改善。当I. galbana 3011与其他三种优势细菌共培养时，包括Algoriphagus sp。，Dinoroseobacter sp。和Oceanicaulis sp。的生长有不同程度的改善。综上所述，目前的工作充分表征了与七个诱饵微藻有关的细菌群落，并对藻类与细菌的相互作用进行了初步探索，这将有助于提高诱饵微藻在其培养过程中的产量和质量。