Objective:

Attention-deficit/hyperactivity disorder (ADHD) in adulthood and dementia with Lewy bodies (DLB) share many cognitive and noncognitive similarities. The overlapping features between both disorders complicate differential diagnosis. The aim of the current systematic review was to compare patterns of neuropsychological profiles in older adults with ADHD and DLB.

Method:

Of the 1989 ADHD-related articles and 1332 DLB-related articles screened, 3 ADHD and 25 DLB articles were retained for qualitative synthesis and review.

Results:

A synthesis of individual study findings revealed isolated working memory deficits for late-life ADHD, and performance deficits in areas of attention, memory, language, and visuoperceptual abilities for DLB. Results were limited by small samples and absence of data in some cognitive domains.

Conclusion:

These initial findings support potentially unique neurocognitive profiles for ADHD in later life and DLB that would enable practitioners to differentially diagnose and appropriately treat older adults presenting with these phenotypically similar disorders.

中文翻译：

---

晚年注意力缺陷/多动障碍和路易体痴呆的神经认知特征的系统评价和比较。

客观的：

成年期注意力缺陷/多动障碍 (ADHD) 和路易体痴呆 (DLB) 有许多认知和非认知相似之处。两种疾病之间的重叠特征使鉴别诊断复杂化。当前系统评价的目的是比较患有 ADHD 和 DLB 的老年人的神经心理特征模式。

方法：

在筛选的 1989 篇 ADHD 相关文章和 1332 篇 DLB 相关文章中，保留了 3 篇 ADHD 和 25 篇 DLB 文章进行定性综合和审查。

结果：

个人研究结果的综合揭示了晚年 ADHD 的孤立工作记忆缺陷，以及 DLB 的注意力、记忆、语言和视觉感知能力方面的表现缺陷。结果受到小样本和某些认知领域数据缺失的限制。

结论：

这些初步发现支持晚年 ADHD 和 DLB 的潜在独特神经认知特征，这将使从业者能够区分诊断和适当治疗出现这些表型相似疾病的老年人。