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Genomic investigation of a suspected multi-drug resistant Klebsiella pneumoniae outbreak in a neonatal care unit in sub-Saharan Africa
bioRxiv - Genomics Pub Date : 2020-08-07 , DOI: 10.1101/2020.08.06.236117
Jennifer Cornick , Patrick Musicha , Chikondi Peno , Ezgi Saeger , Pui-ying Iroh Toh , Aisleen Bennett , Neil Kennedy , Nicholas Feasey , Eva Heinz , Amy K. Cain

A suspected outbreak of multi-drug resistant (MDR) Klebsiella pneumoniae in a Malawian neonatal unit was investigated using whole-genome sequencing. Strain-types, virulence and resistance genes of K. pneumoniae isolated from patients in the hospital over a four-year period were identified. A MDR ST340 clone was implicated as the likely outbreak cause.

中文翻译:

撒哈拉以南非洲新生儿保健部门疑似多重耐药性肺炎克雷伯菌暴发的基因组调查

使用全基因组测序研究了在马拉维新生儿单元中疑似爆发的多药耐药性(MDR)肺炎克雷伯菌。鉴定了从医院的患者中分离出的四年内肺炎克雷伯菌的菌株类型,毒力和耐药基因。MDR ST340克隆可能是爆发原因。
更新日期:2020-08-08
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