ABSTRACT

A simple, one-pot procedure for the synthesis of novel 3-phenyl-3,4-dihydro-2H-benzo[a][1,3] oxazino[5,6-c]phenazine derivatives by four-component coupling reaction between benzo[a]phenazine-5-ol, formaldehyde and amine in the presence of a catalytic amount ZnO-PTA@Fe₃O₄/EN-MIL-101(Cr) nanopowder in ethanol at room temperature under stirring condition. ZnO-PTA@Fe₃O₄/EN-MIL-101(Cr) An inorganic magnetic catalyst was analyzes and described by the XRD, TEM, FESEM, TGA, AFM, VSM and ICP-OES. This study presents simple, efficient, and one-pot multicomponent protocol, which provides several advantages such as short reaction times, high yields, easy working up, chromatography-free technique, catalyst recovery, and reusability are other highlights of this work.

摘要

一种简单的一锅法通过四组分偶联反应合成新型3-苯基-3,4-二氢-2 H-苯并[ a ] [1,3]恶嗪基[5,6- c ]吩嗪衍生物在室温下，在乙醇中，在催化量的ZnO-PTA @ Fe ₃ O ₄ / EN-MIL-101（Cr）纳米粉的存在下，苯并[ a ]吩嗪-5-醇，甲醛和胺之间的关系 ZnO-PTA @ Fe ₃ O ₄/ EN-MIL-101（Cr）通过XRD，TEM，FESEM，TGA，AFM，VSM和ICP-OES分析和描述了无机磁性催化剂。这项研究提出了一种简单，有效和一锅多组分的方案，该方案具有以下几个优点：反应时间短，产率高，易于加工，无色谱技术，催化剂回收率和可重复使用性。