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Epithelial morphogenesis in the perinatal mouse uterus.
Developmental Dynamics ( IF 2.5 ) Pub Date : 2020-08-06 , DOI: 10.1002/dvdy.234
Zer Vue 1, 2 , Richard R Behringer 1, 2
Affiliation  

The uterus is the location where multiple events occur that are required for the start of new life in mammals. The adult uterus contains endometrial or uterine glands that are essential for female fertility. In the mouse, uterine glands are located in the lateral and antimesometrial regions of the uterine horn. Previous three‐dimensional (3D)‐imaging of the adult uterus, its glands, and implanting embryos has been performed by multiple groups, using fluorescent microscopy. Adenogenesis, the formation of uterine glands, initiates after birth. Recently, we created a 3D‐staging system of mouse uterine gland development at postnatal time points, using light sheet fluorescent microscopy. Here, using a similar approach, we examine the morphological changes in the epithelium of the perinatal mouse uterus.

中文翻译:

围产期小鼠子宫上皮形态发生。

子宫是哺乳动物新生命开始所需的多种事件发生的场所。成人子宫含有对女性生育能力至关重要的子宫内膜或子宫腺体。在小鼠中,子宫腺位于子宫角的外侧和逆时体区域。先前,多个小组使用荧光显微镜对成人子宫、腺体和植入胚胎进行了三维 (3D) 成像。腺发生,即子宫腺体的形成,在出生后开始。最近,我们使用光片荧光显微镜创建了小鼠出生后时间点子宫腺发育的 3D 分期系统。在这里,我们使用类似的方法检查围产期小鼠子宫上皮的形态变化。
更新日期:2020-08-06
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