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Scent (Apocrine) Gland Adenocarcinoma in a Wedge-Capped Capuchin Monkey (Cebus olivaceus): Histological and Immunohistochemical Features.
Journal of Comparative Pathology ( IF 0.8 ) Pub Date : 2020-08-07 , DOI: 10.1016/j.jcpa.2020.07.002
A Suárez-Bonnet 1 , S L Priestnall 1 , G A Ramírez 2 , C González-Sánchez 3 , J R Jaber 4
Affiliation  

In humans, apocrine gland tumours encompass a heterogeneous group of uncommon neoplasms with varied and unpredictable biological behaviour. They can be slow-growing lesions, recur after excision, produce lymph node metastasis in up to 50% of cases or lead to tumour-related death. We document a malignant scent adenocarcinoma in a wedge-capped capuchin monkey (Cebus olivaceus). Immunohistochemical labelling revealed complete absence of myoepithelial cells, a finding usually considered a hallmark of malignancy in humans; however, after a 2-year follow-up, the neoplasm had not recurred. This is the first detailed report of the pathology of a spontaneous scent (apocrine) gland adenocarcinoma in a non-human primate.



中文翻译:

楔形帽卷尾猴(Cebus olivaceus)中的气味(顶泌)腺腺癌:组织学和免疫组织化学特征。

在人类中,顶泌腺肿瘤涵盖了一组异质的罕见肿瘤,它们的生物学行为各不相同且无法预测。它们可能是生长缓慢的病变,切除后会复发,在多达50%的病例中会发生淋巴结转移,或导致与肿瘤相关的死亡。我们在楔形帽卷尾猴(Cebus olivaceus)中记录了恶性气味腺癌。免疫组织化学标记显示完全没有肌上皮细胞,这一发现通常被认为是人类恶性肿瘤的标志。然而,经过2年的随访,该肿瘤并未复发。这是非人类灵长类动物中自发性(腺嘌呤)腺癌病理学的第一个详细报告。

更新日期:2020-08-08
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