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Association between ozone air pollution levels and hospitalizations for depression in Taipei: a time-stratified case-crossover study.
Journal of Toxicology and Environmental Health, Part A ( IF 2.6 ) Pub Date : 2020-08-06 , DOI: 10.1080/15287394.2020.1801544
Shang-Shyue Tsai,Ya-Wen Chiu,Yi-Hao Weng,Chun-Yuh Yang

Epidemiologic studies reported an association between exposure to ambient air pollutants and increased mortality rate attributed to suicide and suicide attempts. The investigation sought to determine whether there is an association between short-term ambient ozone (O3) level exposure and daily hospital admissions for depression in Taipei from 2009 to 2013 using a time-stratified case-crossover design. In our single-pollutant model (with no adjustment for other pollutants), the % increase in daily hospital admissions for depression was 12% on warm days and 30% on cool days, per interquartile range (IQR) rise in O3 levels, respectively. Ozone levels were significantly correlated with daily number of depression admissions both on warm and cool days. In our two-pollutant models, O3 levels remained significant after adjusting for other air pollutants, including particulate matter (PM10, PM2.5), sulfur dioxide (SO2), nitrogen dioxide (NO2), and carbon monoxide (CO) both on warm and cool days. Although O3 levels tended to be higher on warm days, admissions for depression were higher on cool days, suggesting that the relationship between O3 concentrations and depression may be affected by temperature. Further study is needed to better understand these findings.



中文翻译:

台北市臭氧空气污染水平与住院抑郁症之间的关联:时间分层的病例交叉研究。

流行病学研究表明,暴露于周围空气污染物与自杀和自杀未遂导致的死亡率上升之间存在关联。该调查旨在通过时间分层病例交叉设计,确定台北市从2009年至2013年因短期臭氧水平(O 3)暴露与抑郁症的每日住院治疗之间是否存在关联。在我们的单一污染物模型中(不对其他污染物进行调整),在温暖的日子里,抑郁症患者每天住院治疗的增加百分比分别为O 3含量每四分位数范围(IQR)上升的12%和凉爽的日子的30%。。在炎热和凉爽的日子里,臭氧水平都与抑郁症的每日入院次数显着相关。在我们的两种污染物模型中,O调整其他空气污染物(包括颗粒物(PM 10,PM 2.5),二氧化硫(SO 2),二氧化氮(NO 2)和一氧化碳(CO))后,在炎热和凉爽的日子里,其3个水平仍然很重要。尽管在温暖的日子中O 3含量往往较高,而在凉爽的日子中抑郁症的发病率较高,这表明O 3浓度与抑郁症之间的关系可能受到温度的影响。需要进一步研究以更好地理解这些发现。

更新日期:2020-08-25
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