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Room-Temperature Palladium(II)-Catalyzed Direct 2-Arylation of Indoles with Tetraarylstannanes
Synlett ( IF 2 ) Pub Date : 2020-08-05 , DOI: 10.1055/s-0040-1707196
Yuxia Liu 1 , Dong Xue 2 , Chao Wang 2 , Linjuan Huang 1
Affiliation  

A palladium(II)-catalyzed direct 2-arylation of indoles by tetraarylstannanes with oxygen (balloon) as the oxidant at room temperature has been developed. Various tetraarylstannanes can be employed as aryl sources for 2-arylation of indoles in up to 89% yield, providing a practical and efficient catalytic protocol for accessing 2-arylindoles.

中文翻译:

室温钯 (II) 催化吲哚与四芳基锡烷的直接 2-芳基化反应

已开发出钯 (II) 催化的四芳基锡烷与氧(气球)作为氧化剂在室温下直接对吲哚进行 2-芳基化反应。各种四芳基锡烷可用作吲哚 2-芳基化的芳基来源,产率高达 89%,为获得 2-芳基吲哚提供了实用且有效的催化方案。
更新日期:2020-08-05
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