Abstract Oxidative stress has been known as a key factor of many disorders affecting human beings. Reactive oxygen species (ROS) attack vital biomolecules, weakening their functioning, thus exacerbating diseases. To attenuate oxidative stress-associated diseases a novel approaches of antioxidant therapies have been anticipated. Antioxidants have the potential to inhibit the propagation and formation of ROS. Dillenia suffruticosa is a medicinal plant, used by the local people for the treatment of various ailments. The study aimed to evaluate the phytochemical screening, antioxidative activity, total phenolic and flavonoid contents of methanol extract, fractions and essential oil of D. suffruticosa. Furthermore, the analysis of phytochemicals was done using gas chromatography and mass spectrometry (GCMS). The result showed the existence of alkaloids, anthraquinones, flavonoids, phytosterol, saponins, tannins, triterpenoids and steroids in the methanol extract and fractions of D. suffruticosa. The butanol fraction and methanol extract showed high phenolic (379.00 ± 9.25 and 277.00 ± 3.50 mg/g) and flavonoid values (74.44 ± 2.18 and 34.83 ± 0.71 mg/g) as compared to ethyl acetate, n-hexane and chloroform fractions. The scavenging capacity of butanol fraction and methanol extract was also higher than other fractions. GCMS analysis indicated the presences of various compounds in methanol extract, fractions and essential oil including methyl glycolate, lauryl acetate, phenol, 2,4-bis (1,1-dimethylethyl), 9,12-octadecadienoic acid, hexadecanoic acid, methyl ester, methyl stearate, phenol, benzyl alcohol, 3-hexen-1-ol, acetate and phytol. Thus, methanol extract, fractions and essential oil of D. suffruticosa leaves mainly contain vital phytochemical and shows good antioxidant activity.

中文翻译：

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地香叶甲醇提取物、甲醇馏分和精油的植物化学研究和抗氧化活性

摘要 氧化应激被认为是影响人类的许多疾病的关键因素。活性氧 (ROS) 攻击重要的生物分子，削弱其功能，从而加剧疾病。为了减轻与氧化应激相关的疾病，人们期待着一种新的抗氧化疗法方法。抗氧化剂有可能抑制 ROS 的传播和形成。Dillenia suffruticosa 是一种药用植物，当地人用它来治疗各种疾病。该研究旨在评估 D. suffruticosa 甲醇提取物、馏分和精油的植物化学筛选、抗氧化活性、总酚和黄酮含量。此外，植物化学物质的分析是使用气相色谱法和质谱法 (GCMS) 进行的。结果表明存在生物碱，D. suffruticosa 甲醇提取物和馏分中的蒽醌、黄酮类化合物、植物甾醇、皂苷、单宁、三萜和类固醇。与乙酸乙酯、正己烷和氯仿馏分相比，丁醇馏分和甲醇提取物显示出较高的酚类物质（379.00 ± 9.25 和 277.00 ± 3.50 毫克/克）和类黄酮值（74.44 ± 2.18 和 34.83 ± 0.71 毫克/克）。丁醇馏分和甲醇提取物的清除能力也高于其他馏分。GCMS 分析表明甲醇提取物、馏分和精油中存在多种化合物，包括乙醇酸甲酯、乙酸月桂酯、苯酚、2,4-双（1,1-二甲基乙基）、9,12-十八碳二烯酸、十六烷酸、甲酯、硬脂酸甲酯、苯酚、苯甲醇、3-己烯-1-醇、乙酸酯和植醇。因此，D.的甲醇提取物、馏分和精油。