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Iron homeostasis disorder in piglet intestine.
Metallomics ( IF 3.4 ) Pub Date : 2020-08-05 , DOI: 10.1039/d0mt00149j
Haoxuan Ding 1 , Xiaonan Yu 1 , Jie Feng 1
Affiliation  

Iron plays an essential role in preventing iron deficiency anemia and ensuring the healthy growth of animals. The special physiological condition of piglets is the main cause of iron deficiency. Iron metabolism in the intestine is the basis for understanding the effects of iron on the health of piglets. In order to scientifically evaluate dietary iron supplementation doses, it is necessary to recognize the effects of iron deficiency and iron overload on piglet intestinal health. Besides, iron as a cofactor is essential for the growth of microorganisms, and microorganisms compete with the host to absorb iron. Under the stress of iron deficiency and iron overload, various control schemes (such as precise nutrition, element balance, elimination of oxidation, etc.) are effective measures to eliminate adverse effects. In this review, we comprehensively review recent findings on the effects of iron deficiency and iron overload on intestinal health. This review will provide a rational design strategy to achieve a reasonable iron supplement, which will guide the use of iron in animal husbandry.

中文翻译:

仔猪肠道铁稳态紊乱。

铁在预防缺铁性贫血和保证动物健康生长方面起着至关重要的作用。仔猪特殊的生理状态是缺铁的主要原因。肠道内的铁代谢是了解铁对仔猪健康影响的基础。为了科学地评估日粮补铁剂量,有必要认识缺铁和铁过载对仔猪肠道健康的影响。此外,铁作为辅因子对微生物的生长至关重要,微生物与宿主竞争吸收铁。在缺铁和铁过载的压力下,各种控制方案(如精准营养、元素平衡、消除氧化等))是消除不利影响的有效措施。在这篇综述中,我们全面回顾了近期关于缺铁和铁过载对肠道健康影响的研究结果。该综述将为实现合理补铁提供合理的设计策略,从而指导畜牧业中铁的使用。
更新日期:2020-08-28
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