Glycoprotein fucosylation, one of the major posttranslational modifications, is known to be highly involved in proteins related to various cancers. Fucosylation occurs in the core and/or outer sites of N−glycopeptides. Elucidation of the fucosylation type of N−glycoproteins is therefore important. However, it has remained a challenge to classify the fucosylation types of N−glycopeptides using collision−induced dissociation (CID) MS/MS spectra.

中文翻译：

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使用质谱中的碰撞诱导解离计算血浆中N-糖蛋白核心和外部岩藻糖基化的计算分类。

糖蛋白岩藻糖基化是主要的翻译后修饰之一，已知高度参与与各种癌症相关的蛋白质。岩藻糖基化发生在N-糖肽的核心和/或外部。因此，阐明岩藻糖基化形式的N-糖蛋白很重要。但是，使用碰撞诱导解离（CID）MS / MS光谱对N-糖肽的岩藻糖基化类型进行分类仍然是一个挑战。