Microbial mediated synthesis of metallic nanoparticles constitutes as effective and promising approach for the development of antibacterial materials in the field of bioengineering and biomedicine. We prepared Cadmium oxide nanoaprticles (CdO NPs) utilizing Penicillium oxalicum, and cadmium acetate solution via coprecipitate method. The elemental composition and morphology of these synthesized CdO NPs were examined through X‐ray diffraction (XRD), UV–Vis absorption spectroscopy, Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM), and Energy dispersive spectroscopy (EDS). Furthermore, we evaluated the bactericidal potential of prepared CdO NPs using Escherichia coli (E.coli), Staphylococcus aureus (S.aureus), Bacillus cereus (B.cereus), and Pseudomonas aeruginosa (P. aeruginosa). Dimethyl sulfoxide was used as negative control while erythromycin was used as positive control. The XRD spectrum revealed cubic crystalline nanoparticles with 22.94 nm size and UV showed absorbance peak at 297 nm with 2.5 eV band gap energy. FTIR depicted O─H and carboxylic groups along with CdO stretching vibration. EDS showed the presence of organic compounds on Cd and O over NPs surface. SEM results revealed the spherical shape of the CdO NPs. The synthesized NPs exhibited highly potent bactericidal activity against selected strains and demonstrated less optical density of 0.086 after 24 hr. Owing to the significant antibacterial activity of CdO NPs, the broad application prospects of these nanoparticles CdO NPs in extensive biomedical applications is indicated.

中文翻译：

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微生物介导的氧化镉纳米颗粒的合成和表征。

金属纳米粒子的微生物介导合成是生物工程和生物医学领域抗菌材料开发的有效且有前景的方法。我们利用草酸青霉和醋酸镉溶液通过共沉淀法制备了氧化镉纳米颗粒 (CdO NPs) 。通过 X 射线衍射 (XRD)、紫外-可见吸收光谱、傅里叶变换红外光谱 (FTIR)、扫描电子显微镜 (SEM) 和能量色散光谱 (EDS) 检查这些合成的 CdO NPs 的元素组成和形貌。此外，我们使用大肠杆菌（E.coli）、金黄色葡萄球菌（E.coli）评估了制备的 CdO NPs 的杀菌潜力（金黄色葡萄球菌），蜡状芽孢杆菌（蜡状芽孢杆菌），和铜绿假单胞菌（绿脓杆菌）。二甲基亚砜用作阴性对照，而红霉素用作阳性对照。XRD 谱显示立方晶体纳米颗粒尺寸为 22.94 nm，UV 在 297 nm 处显示吸收峰，带隙能量为 2.5 eV。FTIR 描绘了 O─H 和羧基以及 CdO 伸缩振动。EDS 显示在 NPs 表面上的 Cd 和 O 上存在有机化合物。SEM 结果揭示了 CdO NPs 的球形形状。合成的 NPs 对选定的菌株表现出高效的杀菌活性，并在 24 小时后显示出 0.086 的较低光密度。由于 CdO NPs 的显着抗菌活性，表明这些纳米颗粒 CdO NPs 在广泛的生物医学应用中具有广阔的应用前景。