OBJECTIVE To examine the peripheral nervous system (PNS) in spinal cord injured (SCI) patients using two novel methods: (1) MScanFit MUNE; a motor unit number estimation method detecting motor unit loss and (2) muscle velocity recovery cycles (MVRCs) measuring muscle membrane properties which has previously shown depolarization of the muscle membrane in denervated muscles. METHODS Thirty chronic SCI patients (lesion above Th10) and twenty-five gender -and age matched healthy controls (HC) were examined. MScanFit was recorded from peroneal nerve to anterior tibial muscle (TA) and tibial nerve to abductor hallucis muscle after excluding localized mononeuropathies. MVRCs were recorded from TA. RESULTS Nerve conduction studies showed mononeuropathy in 8 patients (27%) (sciatic (2), -or peroneal nerve (6)). SCI patients had in average reduced motor unit number compared with HC and prolonged muscle refractory period and reduced supernormality. SIGNIFICANCE A high prevalence of nerve lesion and a diffuse affection of the PNS following SCI are highly relevant findings that should be accounted for when planning neurorehabilitation for persons living with SCI.

中文翻译：

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使用两种新方法检测周围运动神经系统参与慢性脊髓损伤：MScanFit MUNE 和肌肉速度恢复周期

目的 使用两种新方法检查脊髓损伤 (SCI) 患者的周围神经系统 (PNS)：(1) MScanFit MUNE；一种检测运动单位损失的运动单位数量估计方法和（2）测量肌肉膜特性的肌肉速度恢复周期（MVRC），该特性先前已显示去神经支配肌肉中的肌肉膜去极化。方法 检查了 30 名慢性 SCI 患者（Th10 以上的病变）和 25 名性别和年龄匹配的健康对照（HC）。在排除局部单神经病后，从腓神经到胫前肌 (TA) 和胫神经到拇外展肌记录 MScanFit。MVRC 是从 TA 记录的。结果 神经传导研究显示 8 名患者 (27%)（坐骨神经 (2) 或腓神经 (6)）出现单神经病变。与 HC 相比，SCI 患者的平均运动单位数量减少，肌肉不应期延长，超常减少。意义 SCI 后神经损伤的高患病率和 PNS 的弥漫性影响是高度相关的发现，在为 SCI 患者计划神经康复时应该考虑到这些发现。