Orthopedic implants are routinely used for fixation of fractures, correction of deformities, joint replacements, and soft tissue anchorage. Different biomaterials have been engineered for orthopedic implants. Previously, they were designed merely as mechanical devices, now new strategies to enhance bone healing and implant osteointegration via local delivery of molecules and via implant coatings are being developed. These biological coatings should enhance osteointegration and reduce foreign body response or infection. This article reviews current and future orthopedic implants, materials and surface characteristics, biocompatibility, and mechanisms of bacterial adhesion. Additionally, the review is addressing implant-related infection, the main strategies to prevent it and suggest possible future research that may control implant related-infection.

整形外科植入物通常用于固定骨折，矫正畸形，置换关节和软组织固定。已经为骨科植入物设计了不同的生物材料。以前，它们仅设计为机械设备，现在正在开发通过局部递送分子和通过植入物涂层来增强骨骼愈合和植入物骨整合的新策略。这些生物涂层应增强骨整合并减少异物反应或感染。本文介绍了当前和将来的整形外科植入物，材料和表面特性，生物相容性以及细菌粘附的机制。此外，这项审查是针对植入物相关的感染，