Stimuli-responsive polymers exhibit properties that make them ideal candidates for biosensing and molecular diagnostics. Through rational design of polymer composition combined with new polymer functionalization and synthetic strategies, polymers with myriad responsivities, e.g., responses to temperature, pH, biomolecules, CO₂, light, and electricity can be achieved. When these polymers are specifically designed to respond to biomarkers, stimuli-responsive devices/probes, capable of recognizing and transducing analyte signals, can be used to diagnose and treat disease. In this review, we highlight recent state-of-the-art examples of stimuli-responsive polymer-based systems for biosensing and bioimaging.

中文翻译：

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刺激响应的基于聚合物的系统，用于诊断应用。

刺激响应性聚合物具有使其成为生物传感和分子诊断的理想候选物的特性。通过合理设计聚合物组成，结合新的聚合物功能化和合成策略，可以实现具有多种响应性（例如，对温度，pH，生物分子，CO ₂，光和电的响应）的聚合物。当这些聚合物专门设计用于对生物标记物作出反应时，能够识别和转导分析物信号的刺激反应性设备/探针可用于诊断和治疗疾病。在这篇综述中，我们重点介绍了用于生物传感和生物成像的基于刺激响应聚合物的系统的最新技术示例。