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A case series of topiramate-induced angle closure crisis - an ophthalmic emergency.
Cephalalgia ( IF 4.9 ) Pub Date : 2020-08-03 , DOI: 10.1177/0333102420946736
Megha Gopalakrishna 1 , Annamalai Odayappan 1 , Kavitha Srinivasan 1 , Venkatesh Rengaraj 1
Affiliation  

Background

Topiramate is a drug commonly used by physicians. However, it has various systemic and ocular adverse effects. Bilateral angle closure crisis is a potentially blinding adverse reaction that is seldom reported in non-ophthalmic journals.

Objective

This article aims to report a case series of topiramate-induced angle closure crisis in the eyes.

Methods and material

Most patients presented to us with blurred vision and high intra-ocular pressure within days of starting topiramate tablet for headache. However, the attack resolved in those who presented early with prompt treatment, which included stopping topiramate.

Conclusions

Physicians prescribing topiramate must be well aware of this potentially blinding adverse effect. Educating the patient about this possible side effect is important. Timely referral and treatment can prevent blindness in these individuals.



中文翻译:

托吡酯引起的房角闭合危象的病例系列 - 眼科急症。

背景

托吡酯是医生常用的药物。然而,它具有各种全身和眼部副作用。双侧闭角危象是一种潜在的致盲性不良反应,在非眼科期刊中很少报道。

客观的

本文旨在报告托吡酯引起的眼角闭合危象的一系列病例。

方法和材料

大多数患者在开始服用托吡酯片治疗头痛后数天内出现视力模糊和高眼压。然而,那些早期就诊并接受及时治疗(包括停用托吡酯)的患者的发作得到了缓解。

结论

处方托吡酯的医生必须充分意识到这种潜在的致盲不良反应。教育患者有关这种可能的副作用很重要。及时转诊和治疗可以防止这些人失明。

更新日期:2020-08-04
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