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Diagnosis and Treatment of Rheumatic Adverse Events Related to Immune Checkpoint Inhibitors.
Journal of Immunology Research ( IF 4.1 ) Pub Date : 2020-08-04 , DOI: 10.1155/2020/2640273
Yan Xiao 1 , Lin Zeng 1 , Qinglin Shen 1 , Zhiyong Zhou 1 , Zhifang Mao 1 , Qin Wang 1 , Xiquan Zhang 1 , Yingliang Li 2 , Weirong Yao 1
Affiliation  

Immune checkpoint inhibitors (ICIs) have completely changed the treatment of cancer, and they also can cause multiple organ immune-related adverse reactions (irAEs). Among them, rheumatic irAE is less common, mainly including inflammatory arthritis, rheumatic myalgia/giant cell arteritis, inflammatory myopathy, and Sjogren’s syndrome. For oncologists, rheumatism is a relatively new field, and early diagnosis and treatment is very important, and we need to work closely with experienced rheumatologists. In this review, we focused on the incidence, clinical characteristics, and treatment strategies of rheumatic irAE.

中文翻译:

与免疫检查点抑制剂相关的风湿性不良事件的诊断和治疗。

免疫检查点抑制剂(ICIs)完全改变了癌症的治疗方法,它们还可能引起多器官免疫相关的不良反应(irAEs)。其中,风湿性irAE较少见,主要包括炎性关节炎,风湿性肌痛/巨细胞性动脉炎,炎性肌病和干燥综合征。对于肿瘤科医生来说,风湿病是一个相对较新的领域,早期诊断和治疗非常重要,我们需要与经验丰富的风湿病医生密切合作。在这篇综述中,我们集中于风湿性irAE的发生率,临床特征和治疗策略。
更新日期:2020-08-04
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