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The Missing Link between (Un)druggable and Degradable KRAS.
ACS Central Science ( IF 18.2 ) Pub Date : 2020-08-03 , DOI: 10.1021/acscentsci.0c00920
Elena De Vita 1 , Maria Maneiro 1 , Edward W Tate 1
Affiliation  

Design, synthesis, and biological evaluation of the first cell active KRASG12Cchimeric degrader.

中文翻译:

(不可)滥用和可降解的KRAS之间的缺失环节。

第一个具有细胞活性的KRAS G12C嵌合降解子的设计,合成和生物学评估。
更新日期:2020-08-26
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