Abstract In this study, the effect of artemisia (Artemisia annua) leaves extract (ALE) on the immune system, growth performance and antioxidant capacity of common carp (Cyprinus carpio) was investigated. Fish with initial weight (90.32 ± 1.12 g) were fed various levels of ALE (0, 0.5, 1 and 1.5 g/kg) for 8 weeks. The results showed that the growth performance (FW, WG, SGR, PER, and LER) in fish fed 1 g/kg ALE was increased significantly (P<0.05) and the feed conversion ratio (FCR) was improved in fish fed 1 and 1.5 g/kg ALE in comparison to the control group (P<0.05). Skin mucus total protein was higher in fish fed diet containing 0.5 g/kg ALE than the other experimental groups (P<0.05), while the lysozyme, immunoglobulin and protease was increased by increasing of ALE in diets. Respiratory burst activity and serum immune parameters were higher in fish fed 0.5 g/kg ALE than the other treatments (P<0.05). Increasing of catalase (CAT) and decreasing of malondialdehyde (MDA) were observed in fish fed ALE, while glutathione peroxidase (GPx) increased only in fish fed 0.5 g/kg ALE. Hence, it can be concluded that ALE has considerable potential as a natural immunostimulant and growth promotor supplement for the common carp’s aquaculture.

中文翻译：

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饲喂青蒿（Artemisia annua）的鲤鱼（Cyprinus carpio）的皮肤粘膜、血清免疫和抗氧化能力

摘要 本研究研究了青蒿（Artemisia annua）叶提取物（ALE）对鲤鱼（Cyprinus carpio）免疫系统、生长性能和抗氧化能力的影响。给初始体重 (90.32 ± 1.12 g) 的鱼喂食不同水平的 ALE (0、0.5、1 和 1.5 g/kg) 8 周。结果表明，饲喂 1 g/kg ALE 的鱼的生长性能（FW、WG、SGR、PER 和 LER）显着提高（P<0.05），饲料转化率（FCR）在饲喂 1 和与对照组相比，1.5 g/kg ALE (P<0.05)。含0.5 g/kg ALE的鱼饲喂鱼饲料的皮肤粘液总蛋白高于其他实验组（P<0.05），而随着饲料中ALE的增加，溶菌酶、免疫球蛋白和蛋白酶增加。饲喂 0.5 g/kg ALE 的鱼的呼吸爆发活动和血清免疫参数高于其他处理（P<0.05）。在喂食 ALE 的鱼中观察到过氧化氢酶 (CAT) 增加和丙二醛 (MDA) 减少，而谷胱甘肽过氧化物酶 (GPx) 仅在喂食 0.5 g/kg ALE 的鱼中增加。因此，可以得出结论，ALE 作为鲤鱼养殖的天然免疫刺激剂和生长促进剂具有相当大的潜力。