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Dielectric spectroscopy signature for cancer diagnosis: A review
Microwave and Optical Technology Letters ( IF 1.5 ) Pub Date : 2020-08-04 , DOI: 10.1002/mop.32517
Heba Mohamed Fahmy 1 , Amany Mohamed Hamad 1 , Fatma Al‐zahraa Sayed 1 , Youssef S. Abdelaziz 2 , Esraa Samy Abu Serea 3 , Amany Bahaa El‐Din Mustafa 4 , Maha Amir Mohammed 1 , Ayat M. Saadeldin 5
Affiliation  

The effective clinical management of cancer is entirely dependent on the detection at a suitable early time as well as on the proper diagnosis. The main aim of this review is to survey the applications of dielectric spectroscopy in the clinical cancer diagnosis and distinguishing between normal and tumor tissues. This review focuses on the recognition of the biophysical properties of normal and malignant tissues and also of biophysical changes elicited by cancers comprising (breast, liver, thyroid gland, lung, skin, bladder, uterine and ovarian, lung, and prostate) tumors. These biophysical changes are often produced because of the difference in tissue composition, blood flow, and architecture between normal and malignant cells. From the literature, it has been observed that dielectric spectroscopy method can be applied before, during or after tumor surgery; and most of the results are confirmed by conventional analysis such as histopathology. Moreover, by dielectric spectroscopy technique, dielectric parameters, especially conductivity, and permittivity were suggested to be biomarkers for the densification of cancerous patients of the previously mentioned cancer types. It could be concluded that dielectric spectroscopy rapidly provides the biophysical status of normal tissues and cancerous ones and thus can be applied effectively for the early diagnosis and detection of cancers. It could be a promising diagnostic tool in the future.

中文翻译:

介电谱签名在癌症诊断中的应用

癌症的有效临床管理完全取决于在合适的早期检测以及正确的诊断。这篇综述的主要目的是调查介电谱在临床癌症诊断中的应用,并区分正常组织和肿瘤组织。这篇综述着重于对正常和恶性组织的生物物理特性的认识,以及对由(乳腺癌,肝癌,甲状腺癌,肺癌,皮肤癌,膀胱癌,子宫癌和卵巢癌,肺癌和前列腺癌)肿瘤引起的生物物理变化的认识。这些生物物理变化通常是由于正常细胞和恶性细胞之间的组织组成,血流和结构不同而产生的。从文献中可以看出,介电光谱法可以在之前,肿瘤手术期间或之后;并且大多数结果已通过常规分析(如组织病理学)得到证实。此外,通过介电谱技术,介电参数,特别是电导率和介电常数被认为是致密化先前提到的癌症类型的癌症患者的生物标记。可以得出结论,介电光谱法迅速提供了正常组织和癌性组织的生物物理状态,因此可以有效地用于癌症的早期诊断和检测。将来它可能是很有前途的诊断工具。提示介电常数和介电常数是致密化先前提到的癌症类型的癌症患者的生物标志物。可以得出结论,介电光谱法迅速提供了正常组织和癌性组织的生物物理状态,因此可以有效地用于癌症的早期诊断和检测。将来它可能是很有前途的诊断工具。提示介电常数和介电常数是致密化先前提到的癌症类型的癌症患者的生物标志物。可以得出结论,介电光谱法迅速提供了正常组织和癌性组织的生物物理状态,因此可以有效地用于癌症的早期诊断和检测。将来它可能是很有前途的诊断工具。
更新日期:2020-10-07
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