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Cryo-EM Uncovers Atomic Details for Loading Cell-Killing Enzymes to the Anthrax Toxin Pretranslocation Complex.
Structure ( IF 5.7 ) Pub Date : 2020-08-04 , DOI: 10.1016/j.str.2020.07.008
Xiaodan Ni 1 , Jiansen Jiang 1
Affiliation  

In this issue of Structure, Zhou et al. report the structures of full-length lethal and edema factors, the cytotoxic components of the deadly anthrax toxin, in complex with the toxin’s cell binding and delivery module, the protective antigen prechannel, providing an atomic description for the toxin recruitment prior to translocation.



中文翻译:

Cryo-EM揭示了将细胞杀伤酶装载到炭疽毒素预转运复合物中的原子细节。

在本期《结构》中,Zhou等人。报道了致命的炭疽和毒素的全长致死和水肿因子的结构,与毒素的细胞结合和传递模块,保护性抗原预通道结合在一起,为易位之前的毒素募集提供了原子描述。

更新日期:2020-08-04
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