Abstract The leaf of Physalis angulata L. is widely used in Ghana by rural and urban dwellers for the treatment of wounds. This study sought to evaluate the anti-inflammatory and wound healing activities of methanol leaf extract of Physalis angulata L. (PAL). Preliminary phytochemical screening was used to determine the phytochemical constituents in this plant material. Anti-inflammatory activity of extract concentrations at doses of 30, 100 and 300 mg/kg body weight of the rats, were determined by carrageenan-induced foot oedema model in rats. The wound healing activity was studied using the excision wound model in rats with concentrations of 1.25, 2.5, 5, 10% w/w. The progression and microscopic bedding of wound healing was determined by the periodic assessment of the contraction of excision wounds and histological studies. Preliminary phytochemical screening of the PAL and its pulverized leaves revealed the presence of saponins, tannins, flavonoids, reducing sugars, anthracenosides and carbohydrates in the extracts. The anti-inflammatory activity of the extract at 100 and 300 mg/kg caused a significant (p

中文翻译：

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酸浆甲醇叶提取物的抗炎和伤口愈合特性。

摘要 Physalis angulata L. 的叶子在加纳被农村和城市居民广泛用于治疗伤口。本研究旨在评估 Physalis angulata L. (PAL) 甲醇叶提取物的抗炎和伤口愈合活性。初步植物化学筛选用于确定该植物材料中的植物化学成分。通过角叉菜胶诱导的大鼠足部水肿模型确定提取物浓度为 30、100 和 300 mg/kg 大鼠体重的抗炎活性。使用浓度为 1.25、2.5、5、10% w/w 的大鼠切除伤口模型研究伤口愈合活性。通过定期评估切除伤口的收缩和组织学研究来确定伤口愈合的进展和微观层面。PAL 及其粉碎叶的初步植物化学筛选显示提取物中存在皂苷、单宁、黄酮类化合物、还原糖、蒽苷和碳水化合物。提取物在 100 和 300 mg/kg 时的抗炎活性导致显着（p