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New benzoic acid derivatives from Cassia italica growing in Saudi Arabia and their antioxidant activity.
Saudi Pharmaceutical Journal ( IF 4.1 ) Pub Date : 2020-08-03 , DOI: 10.1016/j.jsps.2020.07.012
Rwaida A Al-Haidari 1 , Mai M Al-Oqail 2
Affiliation  

Two new benzoic acid derivatives: 1-p-hydroxy benzoyl-3-palmitoyl glycerol (1) and 6 -p-hydroxy benzoyl daucosterol (2), along with scutellarein-6-methyl ether (3), quercetin (4), and rutin (5) had been separated from Cassia italica (Fabaceae) aerial parts from EtOAc fraction. Their characterisation was accomplished by various spectroscopic techniques and by comparing with the published data. The Ethyl acetate (EtOAc) fraction and compounds 15 had been assessed for their antioxidant potential utilizing DPPH assay. They had significant antioxidant capacities with activity ranged from 19.7 to 95.8%, in comparison to butylated hydroxyanisole (BHA) (93.8%). These findings could provide a further evidence to support the traditional use of C. italica for the treatment of chronic or degenerative illnesses.



中文翻译:

来自沙特阿拉伯的决明子的新苯甲酸衍生物及其抗氧化活性。

两种新的苯甲酸衍生物:1-羟基苯甲酰基-3-棕榈酰基甘油 ( 1 ) 和 6-羟基苯甲酰基胡萝卜甾醇 ( 2 ),以及灯盏花素-6-甲基醚 ( 3 )、槲皮素 ( 4 ) 和芦丁 ( 5 ) 已从 EtOAc 馏分中从Cassia italica (Fabaceae) 地上部分中分离出来。它们的表征是通过各种光谱技术并通过与公布的数据进行比较来完成的。乙酸乙酯 (EtOAc) 馏分和化合物15已经使用 DPPH 测定法评估了它们的抗氧化潜力。与丁基羟基茴香醚 (BHA) (93.8%) 相比,它们具有显着的抗氧化能力,活性范围为 19.7% 至 95.8%。这些发现可以提供进一步的证据来支持传统使用斜纹衣草治疗慢性或退行性疾病。

更新日期:2020-08-03
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