The precise mechanisms of free fatty acid (FFA) uptake in the vascular endothelium are unclear. In this issue of Cell Metabolism, Ibrahim et al. (2020) discover that FFA uptake is partially mediated by a vectorial, ER-mitochondria link, in which mitochondrial ATP production is locally used for the acyl-CoA synthetase activity of the ER-located fatty acid transport protein 4.

中文翻译：

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向量，ER-线粒体链接到血管内皮中的能量稳态。

尚不清楚血管内皮中游离脂肪酸（FFA）摄取的确切机制。在本期《细胞代谢》一书中，易卜拉欣等人。（2020）发现，FFA摄取部分是由矢量，ER-线粒体连接介导的，其中线粒体ATP的产生局部用于ER定位的脂肪酸转运蛋白4的酰基辅酶A合成酶活性。