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Make killers sweeter: targeting metabolic checkpoints of NK cells.
Nature Immunology ( IF 30.5 ) Pub Date : 2020-08-03 , DOI: 10.1038/s41590-020-0738-x
Haiming Wei 1, 2 , Binqing Fu 1, 2
Affiliation  

Group 2 innate lymphoid cells (ILC2s) closely intersect with antitumor immunity. A new study describes how activation of lung-resident ILC2s orchestrates the suppression of natural killer cell–mediated innate antitumor immunity via an eosinophil-mediated metabolic mechanism.

中文翻译:

使杀手更甜:针对NK细胞的代谢检查点。

第2组先天淋巴样细胞(ILC2s)与抗肿瘤免疫力紧密相交。一项新的研究描述了驻留在肺部的ILC2的激活如何通过嗜酸性粒细胞介导的代谢机制来抑制自然杀伤细胞介导的先天抗肿瘤免疫。
更新日期:2020-08-03
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