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A bridge between melanoma cell states.
Nature Cell Biology ( IF 21.3 ) Pub Date : 2020-08-03 , DOI: 10.1038/s41556-020-0556-2
Nicole M Aiello-Couzo 1 , Yibin Kang 1
Affiliation  

Cellular plasticity allows tumours to adapt to and overcome therapeutic challenges. A recent study uncovered the gene regulatory networks that govern cell states and phenotype switching in melanoma, opening up possibilities to therapeutically target cell states or phenotypic plasticity to render melanoma cells more vulnerable to treatment.

中文翻译:

黑色素瘤细胞状态之间的桥梁。

细胞可塑性使肿瘤适应并克服治疗挑战。最近的一项研究发现了控制黑素瘤细胞状态和表型转换的基因调控网络,为治疗性靶向细胞状态或表型可塑性打开了可能性,使黑素瘤细胞更容易受到治疗。
更新日期:2020-08-03
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