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Complex Method of CT and Morphological Examination of Placental Angioarchitechtonics
Bulletin of Experimental Biology and Medicine ( IF 0.7 ) Pub Date : 2020-07-01 , DOI: 10.1007/s10517-020-04897-4
A I Shchegolev 1 , U N Tumanova 1 , V M Lyapin 1 , A V Kozlova 1 , V G Bychenko 1 , G T Sukhikh 1
Affiliation  

We propose an original method of complex assessment of the placental angioarchitechtonics based on computed tomography (CT) and morphological examination. A prerequisite condition of successful examination and assessment of the placental angioarchitechtonics is the pre-preparative stage including clearing of the placental and umbilical cord vessels from blood clots by placement of placenta into 10% hypertonic NaCl solution and then on a hygroscopic substrate. The major stage of this method is injection of contrast staining mixtures into the umbilical vessels followed by CT. The concentration of radiocontrast agent in water solution of gouache should be 70% for arteries and 15% for veins. The volumes of mixtures for contrast staining should be calculated according to the weight of the placenta. The contrast staining mixture was first injected into the catheterized unpaired umbilical vein, and then into both umbilical arteries. Each injection of the contrast staining mixture was visually inspected; then branching of the stained vessel was photographed and scanned by CT. The CT scans were used to construct 3D models of placental vessels and spectral color maps, which made it possible to examine the peculiarities of placental angioarchitechtonics, to identify and evaluate anastomoses of placental vessels, and to establish the type of these anastomoses.

中文翻译:

胎盘血管构筑物CT与形态学检查的复合方法

我们提出了一种基于计算机断层扫描 (CT) 和形态学检查对胎盘血管结构进行复杂评估的原始方法。成功检查和评估胎盘血管结构的先决条件是准备阶段,包括通过将胎盘置于 10% 高渗 NaCl 溶液中,然后置于吸湿基质上,清除血块中的胎盘和脐带血管。这种方法的主要阶段是将对比染色混合物注射到脐带血管中,然后进行 CT。水粉颜料水溶液中放射性造影剂的浓度应为动脉为70%,静脉为15%。用于对比染色的混合物体积应根据胎盘的重量计算。对比染色混合物首先注入导管未配对的脐静脉,然后注入两条脐动脉。目视检查对比染色混合物的每次注射;然后对染色血管的分支进行拍照并通过 CT 扫描。CT 扫描用于构建胎盘血管的 3D 模型和光谱彩色图,这使得检查胎盘血管结构的特性、识别和评估胎盘血管的吻合以及确定这些吻合的类型成为可能。
更新日期:2020-07-01
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