Although pre-exposure prophylaxis (PrEP) could substantially reduce the risk of HIV acquisition among adolescent cisgender men who have sex with men (cisMSM), various barriers faced by people of color, particularly within the southern region of the U.S., may lead to racial disparities in the utilization of PrEP. Few studies, however, have explored racial/ethnic differences in PrEP use by geographic setting among adolescent cisMSM. We conducted a cross-sectional analysis examining racial disparities in PrEP use among cisMSM ages 15-24 years in New Orleans, Louisiana, and Los Angeles, California recruited between May, 2017 and September, 2019. The odds of PrEP use among AA adolescents were considerably lower than White adolescents in New Orleans (OR (95% CI): 0.24 (0.10, 0.53)), although we did not find evidence of differences in Los Angeles. Our findings underscore the need for targeted interventions to promote PrEP use among adolescent MSM, particularly among AA adolescent cisMSM living in the southern region of U.S.

中文翻译：

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两个城市的故事：探索种族/民族和地理环境对青少年顺性别 MSM 使用 PrEP 的作用。

尽管暴露前预防 (PrEP) 可以显着降低与男性发生性关系的青少年顺性别男性 (cisMSM) 感染 HIV 的风险，但有色人种面临的各种障碍，尤其是在美国南部地区，可能会导致种族歧视。 PrEP 使用的差异。然而，很少有研究通过地理环境探讨青少年 cisMSM 中 PrEP 使用的种族/民族差异。我们进行了一项横断面分析，检查了 2017 年 5 月至 2019 年 9 月期间在路易斯安那州新奥尔良和加利福尼亚州洛杉矶招募的 15-24 岁 cisMSM 之间使用 PrEP 的种族差异。AA 青少年使用 PrEP 的几率是远低于新奥尔良的白人青少年（OR (95% CI)：0.24 (0.10, 0.53)），尽管我们没有发现洛杉矶存在差异的证据。