The attributes of an HIV microbicide may affect its acceptability, uptake and use. Quatro, a clinical study with a qualitative component, was conducted to elicit input from end-users and key informants (KIs) on four different placebo vaginal microbicide delivery forms; fast dissolving insert, ring, film and gel. In-depth interviews and focus group discussions were conducted with young women, their male partners and KIs, to explore acceptability and preferences of the four placebo products, with the intention of improving product attributes, adherence, and consequently, long term effectiveness. None of the four microbicide delivery forms stood well above others as the most preferred. Product attributes; long-action, ease of use, invisibility, female initiated and non-interference during sex were favourable in both countries. Despite preference for the long-action, on-demand products were the most liked by women. Qualitative data from the Quatro study provided rich feedback on specific attributes important to the acceptability of four HIV prevention product platforms currently in development, enabling more informed and guided product development efforts moving forward.

中文翻译：

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在南非和津巴布韦，女性，男性伴侣和主要信息提供者中用于预防HIV的阴道分娩形式的偏爱和可接受性：定性发现。

HIV杀菌剂的属性可能会影响其可接受性，吸收和使用。Quatro是一项具有定性成分的临床研究，旨在从最终用户和关键信息提供者（KIs）处获得四种不同的安慰剂阴道杀菌剂阴道释放形式的信息；快速溶解的插入物，环，薄膜和凝胶。与年轻女性，其男性伴侣和KIs进行了深入访谈和焦点小组讨论，以探讨四种安慰剂产品的可接受性和偏好，目的是改善产品属性，依从性和长期效果。四种杀微生物剂的传递形式中没有一个比其他形式更好。产品属性; 长效，易用性，隐形性，女性引发的性行为以及在性交时不受干扰在两个国家都是有利的。尽管偏爱长效，按需产品仍是女性最喜欢的产品。Quatro研究的定性数据提供了对特定属性的丰富反馈，这些属性对当前正在开发的四个HIV预防产品平台的可接受性很重要，从而使更明智和有指导性的产品开发工作得以开展。