当前位置：
X-MOL 学术
›
Cardiovasc. Ultrasound
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Left atrial spontaneous echo contrast occurring in patients with low CHADS2 or CHA2DS2-VASc scores.
Cardiovascular Ultrasound ( IF 1.9 ) Pub Date : 2020-08-01 , DOI: 10.1186/s12947-020-00213-2 Kanako Akamatsu 1 , Takahide Ito 1 , Michishige Ozeki 1 , Masatoshi Miyamura 1 , Koichi Sohmiya 1 , Masaaki Hoshiga 1
Cardiovascular Ultrasound ( IF 1.9 ) Pub Date : 2020-08-01 , DOI: 10.1186/s12947-020-00213-2 Kanako Akamatsu 1 , Takahide Ito 1 , Michishige Ozeki 1 , Masatoshi Miyamura 1 , Koichi Sohmiya 1 , Masaaki Hoshiga 1
Affiliation
Left atrial spontaneous echo contrast (LASEC) is common in patients with atrial fibrillation (AF), although scarce information exists on LASEC occurring in nonvalvular AF patients who have low thromboembolic risk scores. We therefore examined prevalence and determinants of LASEC under low CHADS2 or CHA2DS2-VASc scores in these patients. Among 713 patients who underwent transesophageal echocardiography, 349 with a CHADS2 score < 2 (CHADS2 group) (93 women, mean age 65 years) and 221 with a CHA2DS2-VASc score < 2 (CHA2DS2-VASc group) (39 women, mean age 62 years) were separately examined for clinical and echocardiographic findings. LASEC was found in 77 patients of CHADS2 group (22%) and in 41 of CHA2DS2-VASc group (19%). Multivariate logistic regression analysis, adjusted for several parameters including non-paroxysmal AF, LA enlargement (LA diameter ≥ 50 mm), left ventricular (LV) hypertrophy, and an elevated B-type natriuretic peptide (BNP) (BNP ≥200 pg/mL) revealed that for CHADS2 group, non-paroxysmal AF (Odds ratio 5.65, 95%CI 3.08–10.5, P < 0.001), BNP elevation (Odds ratio 3.42, 95%CI 1.29–9.06, P = 0.013), and LV hypertrophy (Odds ratio 2.26, 95%CI 1.19–4.28, P = 0.013) were significant independent determinants of LASEC, and that for CHA2DS2-VASc group, non-paroxysmal AF (Odds ratio 3.38, 95%CI 1.51–7.54, P = 0.003) and LV hypertrophy (Odds ratio 2.53, 95%CI 1.13–5.70, P = 0.025) were significant independent determinants of LASEC. LASEC was present in a considerable proportion of patients with nonvalvular AF under low thromboembolic risk scores. Information on AF chronicity, BNP, and LV hypertrophy might help identify patients at risk for thromboembolism, although large-scale studies are necessary to confirm our observations.
中文翻译：
CHADS2或CHA2DS2-VASc评分低的患者发生左心房自发回声对比。
左心房自发回声对比（LASEC）在房颤患者中很常见，尽管在血栓栓塞风险评分低的非瓣膜性AF患者中存在关于LASEC的信息很少。因此，我们检查了这些患者在低CHADS2或CHA2DS2-VASc评分下的LASEC患病率和决定因素。在713例经食管超声心动图检查的患者中，349例CHADS2评分<2（CHADS2组）（93名女性，平均年龄65岁）和221例CHA2DS2-VASc评分<2（CHA2DS2-VASc组）（39例女性，平均年龄62岁）分别进行了临床和超声心动图检查。在CHADS2组的77例患者（22％）和CHA2DS2-VASc组的41例（19％）中发现了LASEC。多元logistic回归分析，针对包括非阵发性房颤，LA增大（LA直径≥50 mm），左心室（LV）肥大和B型钠尿肽（BNP）升高（BNP≥200pg / mL）显示，CHADS2组为非阵发性AF（赔率比为5.65 ，95％CI 3.08–10.5，P <0.001），BNP升高（赔率3.42、95％CI 1.29–9.06，P = 0.013）和左心肥大（赔率2.26、95％CI 1.19–4.28，P = 0.013） ）是LASEC的重要独立决定因素，而对于CHA2DS2-VASc组，非阵发性AF（赔率3.38，95％CI 1.51-7.54，P = 0.003）和LV肥大（赔率2.53，95％CI 1.13–5.70） ，P = 0.025）是LASEC的重要独立决定因素。在低血栓栓塞风险评分下，相当一部分非瓣膜性房颤患者存在LASEC。有关AF慢性，BNP和LV肥大的信息可能有助于确定有血栓栓塞风险的患者，
更新日期：2020-08-02
中文翻译：
CHADS2或CHA2DS2-VASc评分低的患者发生左心房自发回声对比。
左心房自发回声对比（LASEC）在房颤患者中很常见，尽管在血栓栓塞风险评分低的非瓣膜性AF患者中存在关于LASEC的信息很少。因此，我们检查了这些患者在低CHADS2或CHA2DS2-VASc评分下的LASEC患病率和决定因素。在713例经食管超声心动图检查的患者中，349例CHADS2评分<2（CHADS2组）（93名女性，平均年龄65岁）和221例CHA2DS2-VASc评分<2（CHA2DS2-VASc组）（39例女性，平均年龄62岁）分别进行了临床和超声心动图检查。在CHADS2组的77例患者（22％）和CHA2DS2-VASc组的41例（19％）中发现了LASEC。多元logistic回归分析，针对包括非阵发性房颤，LA增大（LA直径≥50 mm），左心室（LV）肥大和B型钠尿肽（BNP）升高（BNP≥200pg / mL）显示，CHADS2组为非阵发性AF（赔率比为5.65 ，95％CI 3.08–10.5，P <0.001），BNP升高（赔率3.42、95％CI 1.29–9.06，P = 0.013）和左心肥大（赔率2.26、95％CI 1.19–4.28，P = 0.013） ）是LASEC的重要独立决定因素，而对于CHA2DS2-VASc组，非阵发性AF（赔率3.38，95％CI 1.51-7.54，P = 0.003）和LV肥大（赔率2.53，95％CI 1.13–5.70） ，P = 0.025）是LASEC的重要独立决定因素。在低血栓栓塞风险评分下，相当一部分非瓣膜性房颤患者存在LASEC。有关AF慢性，BNP和LV肥大的信息可能有助于确定有血栓栓塞风险的患者，
京公网安备 11010802027423号