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A review of biological effects and treatments of inhaled depleted uranium aerosol.
Journal of Environmental Radioactivity ( IF 2.3 ) Pub Date : 2020-08-02 , DOI: 10.1016/j.jenvrad.2020.106357
Yonghong Ran 1 , Shuang Wang 1 , Yazhen Zhao 1 , Juan Li 1 , Xinze Ran 1 , Yuhui Hao 1
Affiliation  

Depleted uranium (DU) is primarily used for DU bombs and DU tanks in the military. Aerosol inhalation is considered the primary route of DU exposure. Although laboratory tests have confirmed that inhalation of DU aerosol can cause lung, kidney, and other organ damage, epidemiological studies have found no conclusive evidence that persons in areas with prolonged exposure to DU-containing bombs are affected. After the body inhaled DU aerosols, we first clear the insoluble DU through whole-lung lavage (WLL). Then we eliminate the soluble uranium by the chelating agent. Besides, reducing DU damage to tissues and cells through drugs is also an important treatment method. In future research, emphasis should be placed on the damage mechanism of DU aerosol, the laboratory and clinical research of DU chelating agents, the research on the combination of DU chelating agent and WLL, and the research and development of new drugs to prevent DU damage.



中文翻译:

吸入贫铀气雾剂的生物学效应和治疗方法的综述。

贫铀(DU)主要用于军用DU炸弹和DU坦克。吸入气雾剂被认为是DU暴露的主要途径。尽管实验室测试已确认吸入DU气雾剂可导致肺,肾和其他器官损害,但流行病学研究尚未发现确凿的证据表明长期接触含DU炸弹的地区的人受到影响。人体吸入DU气雾剂后,我们首先通过全肺灌洗(WLL)清除不溶性DU。然后我们用螯合剂消除了可溶性铀。此外,通过药物减少DU对组织和细胞的损害也是重要的治疗方法。在未来的研究中,应重点研究DU气雾剂的破坏机理,DU螯合剂的实验室和临床研究,

更新日期:2020-08-02
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