The fast‐paced field of synthetic biology is fundamentally changing the global biosecurity framework. Current biosecurity regulations and strategies are based on previous governance paradigms for pathogen‐oriented security, recombinant DNA research, and broader concerns related to genetically modified organisms (GMO s). Many scholarly discussions and biosecurity practitioners are therefore concerned that synthetic biology outpaces established biosafety and biosecurity measures to prevent deliberate and malicious or inadvertent and accidental misuse of synthetic biology's processes or products. This commentary proposes three strategies to improve biosecurity: Security must be treated as an investment in the future applicability of the technology; social scientists and policy makers should be engaged early in technology development and forecasting; and coordination among global stakeholders is necessary to ensure acceptable levels of risk.

中文翻译：

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建立合成生物学的生物安全性。

合成生物学快速发展的领域正在从根本上改变全球生物安全框架。当前的生物安全法规和策略基于以前的治理范式，以针对病原体的安全性，重组DNA研究以及与转基因生物（GMO）有关的广泛关注。因此，许多学术讨论和生物安全从业者都担心，合成生物学要超过既定的生物安全和生物安全措施，以防止故意和恶意或无意和意外滥用合成生物学的过程或产品。该评论提出了三种改善生物安全性的策略：必须将安全性视为对该技术未来适用性的投资；社会科学家和政策制定者应尽早参与技术开发和预测；全球利益相关者之间的协调对于确保可接受的风险水平是必要的。