The detection of specific pesticides on food products is essential as these substances pose health risks due to their toxicity. The use of surface-enhanced Raman spectroscopy (SERS) takes advantage of the straightforward technique to obtain fingerprint spectra of target analytes. In this study, SERS-active substrates are made using Au nanoparticles (NPs) coated with a layer of polymer and followed by imprinting with a pesticide–Cypermethrin, as a molecularly imprinted polymer (MIP). Cypermethrin was eventually removed and formed as template cavities, then denoted as Au NP/MIP, to capture the analogous molecules. The captured molecules situated in-between the areas of high electromagnetic field formed by plasmonic Au NPs result in an effect of SERS. The formation of Au NP/MIP was, respectively, studied through morphological analysis using transmission electron microscopy (TEM) and compositional analysis using X-ray photoelectron spectroscopy (XPS). Two relatively similar pesticides, Cypermethrin and Permethrin, were used as analytes. The results showed that Au NP/MIP was competent to detect both similar molecules despite the imprint being made only by Cypermethrin. Nevertheless, Au NP/MIP has a limited number of imprinted cavities that result in sensing only low concentrations of a pesticide solution. Au NP/MIP is thus a specific design for detecting analogous molecules similar to its template structure.

中文翻译：

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氯氰菊酯在金纳米颗粒上的表面印迹层作为检测模板农药分子的特异性和选择性涂层

食品中特定农药的检测至关重要，因为这些物质由于毒性而对健康构成威胁。表面增强拉曼光谱（SERS）的使用利用了简单的技术来获得目标分析物的指纹图谱。在这项研究中，SERS活性底物是用涂有一层聚合物的金纳米颗粒（NP）制成，然后用农药氯氰菊酯作为分子印迹聚合物（MIP）进行印迹。最终除去氯氰菊酯并形成模板腔，然后表示为Au NP / MIP，以捕获类似分子。被等离子体Au NPs形成的高电磁场区域之间的捕获分子导致SERS效应。金NP / MIP的形成分别是 通过使用透射电子显微镜（TEM）的形态分析和使用X射线光电子能谱（XPS）的成分分析进行了研究。两种相对相似的农药氯氰菊酯和氯菊酯被用作分析物。结果表明，尽管仅由氯氰菊酯制成印迹，Au NP / MIP仍能够检测两种相似的分子。尽管如此，Au NP / MIP的印迹腔数量有限，导致仅感测低浓度的农药溶液。因此，Au NP / MIP是一种用于检测类似于其模板结构的类似分子的特定设计。结果表明，尽管仅由氯氰菊酯制成印迹，Au NP / MIP仍能够检测两种相似的分子。尽管如此，Au NP / MIP的印迹腔数量有限，导致仅感测低浓度的农药溶液。因此，Au NP / MIP是一种用于检测类似于其模板结构的类似分子的特定设计。结果表明，尽管仅由氯氰菊酯制成印迹，Au NP / MIP仍能够检测两种相似的分子。尽管如此，Au NP / MIP的印迹腔数量有限，导致仅感测低浓度的农药溶液。因此，Au NP / MIP是一种用于检测类似于其模板结构的类似分子的特定设计。