Transition‐metal‐catalyzed 1,2‐carbohalo‐functionalization reactions of C−C multiple bonds have emerged rapidly over the past decade as a powerful tool for generating a new carbon‐carbon and carbon‐halogen bond via transposition of an existing carbon‐halogen σ bond. Exploring this highly efficient mode of carbon‐carbon multiple bond difunctionalization, various research groups have established novel strategies for the synthesis of organohalides by utilizing wide variety of transition metal catalysts under mild reaction conditions, avoiding stoichiometric waste of by‐products, and with improved levels of chemo‐, regio‐, and stereoselectivities. Most of the 1,2‐carbohalo‐functionalization reactions involve either the carbon‐halogen reductive elimination mechanism or the atom transfer radical addition (ATRA) mechanism. This review summarizes the recent progress in the area of transition‐metal‐catalyzed intra‐ and intermolecular 1,2‐carbohalo‐functionalization reactions of carbon‐carbon multiple bonds and explicates the underlying potentiality and challenges within the field.

中文翻译：

---

过渡金属催化的C-C多键的碳卤化1,2-双官能化

过去十年中，CC多重键的过渡金属催化的1,2-碳卤代官能化反应迅速出现，成为通过现有碳-卤素置换产生新的碳-碳和碳-卤素键的有力工具。 σ键。为了探索这种高效的碳-碳多键双官能化模式，各个研究小组建立了新的有机卤化物合成策略，方法是在温和的反应条件下利用各种过渡金属催化剂，避免化学计量的副产物浪费，并提高其水平。化学，区域和立体选择性 大多数1,2-碳卤官能化反应涉及碳-卤素还原消除机理或原子转移自由基加成（ATRA）机制。