In widespread use in commercial products as plasticizers, phthalic acid esters (phthalates) have worried researchers and society in general, given the negative impacts on living organisms, especially human health. Since they are not chemically linked to the polymeric matrix, their migration is evident for samples that come into contact with plastics that contain them, such as water, food and saliva. In this work, a new strategy is described, named parallel-disposable pipette extraction (Pa-DPX), in a fast, efficient and robust analytical method using five simultaneous extractions for the determination of migration of 6 phthalates from common plastic materials (children's toys, school supplies, dog toys and oral contact items) to saliva simulant, using gas chromatography-mass spectrometry (GC-MS). The optimized conditions were 5 extraction cycles with 1600 μL of saliva simulant and desorption with 200 μL of ethyl acetate using 5 cycles with the same aliquot. The calibration curves resulted in determination coefficients higher than 0.9915, limits of detection at 1.5 μg L⁻¹, and the quantification limits were 5.0 μg L⁻¹. Excellent results were obtained for repeatability (relative standard deviation ranging from 8.7% to 20.1% for 5 μg L⁻¹) and intermediate precision, varying the day of analyses (7.9%–16.2%). The analyte recovery ranged from 75% to 114% for two different samples, in four different levels of concentration. The Pa-DPX-GC-MS method was successfully applied to determine the migration of PAE from 21 samples. At least one PAE was detected in 81% of samples, and di-n-octyl phthalate was found in higher concentration, achieving the migration of almost 30 μg per g of sample.

邻苯二甲酸酯（邻苯二甲酸酯）被广泛用于商业产品中作为增塑剂，这给研究人员和整个社会带来了困扰，因为它们对生物体，特别是对人类健康的负面影响。由于它们未化学键合到聚合物基体上，因此对于与包含水，食物和唾液的塑料接触的样品，它们的迁移很明显。在这项工作中，描述了一种新的策略，称为平行一次性移液器提取（Pa-DPX），该方法使用五种同时提取的快速，高效和鲁棒的分析方法来测定常见塑料材料（儿童玩具）中6种邻苯二甲酸酯的迁移。 ，学校用品，狗玩具和口腔接触物品），使用气相色谱-质谱（GC-MS）来模拟唾液。优化的条件是用1600μL唾液模拟物进行5个提取循环，并使用5个循环以等分试样用200μL乙酸乙酯解吸。校准曲线导致测定系数高于0.9915，检测限为1.5μgL^-1，定量限为5.0μgL ^-1。重复性（5μgL ^-1的相对标准偏差范围为8.7％至20.1％）和中等精度（改变分析日的范围为7.9％–16.2％）获得了极好的结果。对于两种不同的样品，在四个不同的浓度水平下，分析物的回收率范围为75％至114％。Pa-DPX-GC-MS方法已成功应用于确定21个样品中PAE的迁移。在81％的样品中检测到至少一种PAE，并且发现邻苯二甲酸二正辛酯的浓度更高，每克样品几乎实现了30μg的迁移。