Rosemary extract (RE) has significant antioxidant and antibacterial properties; however, the application of RE to areas with an aqueous solution is limited due to its poor solubility. There is a need for research focused on finding a method to improve water solubility for incorporating RE into aqueous systems, such as food and cosmetic. Therefore, in this study, the micellar solubilization of RE is conducted using four types of surfactants (Tween 20, polyglyceryl-10-laurate, polyglyceryl-10-myristate, and polyglyceryl-10-monooleate) to increase the water solubility of RE and the effects of various surfactant types and concentration on solubility were investigated. Antibacterial activities of the mixture solutions containing RE and surfactants were also examined. The water solubility of RE significantly improved when surfactants were added into the RE solution and especially in polyglyceryl-10-monooleate, with the longest tail, was the most effective for increasing solubility. In terms of the antibacterial effect on Bacillus subtilis, it was observed that a relatively lower concentration of surfactants was effective. The results of this study provide useful information for the development of a new RE-loaded delivery system for food and cosmetic application.

迷迭香提取物 (RE) 具有显着的抗氧化和抗菌特性；然而，由于溶解性差，RE在水溶液领域的应用受到限制。需要进行研究，重点是寻找一种提高水溶性的方法，以便将 RE 加入到水性体系中，例如食品和化妆品。因此，在本研究中，使用四种类型的表面活性剂（吐温 20、聚甘油 10-月桂酸酯、聚甘油 10-肉豆蔻酸酯和聚甘油 10-单油酸酯）对稀土进行胶束增溶，以增加稀土的水溶性和研究了各种表面活性剂类型和浓度对溶解度的影响。还检测了含有稀土和表面活性剂的混合溶液的抗菌活性。当表面活性剂加入到 RE 溶液中时，RE 的水溶性显着提高，尤其是在聚甘油 10-单油酸酯中，尾部最长，对增加溶解度最有效。从抗菌作用来看枯草芽孢杆菌，观察到相对较低浓度的表面活性剂是有效的。这项研究的结果为开发用于食品和化妆品应用的新型 RE 负载输送系统提供了有用的信息。