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Incidence of deep venous thrombosis (DVT) of the lower extremity in patients undergoing surgeries for ankle fractures.
Journal of Orthopaedic Surgery and Research ( IF 2.6 ) Pub Date : 2020-07-31 , DOI: 10.1186/s13018-020-01809-0
Luo Zixuan 1 , Wei Chen 2, 3 , Yansen Li 1 , Xiaomeng Wang 1 , Weili Zhang 1 , Yanbin Zhu 2, 3 , Fengqi Zhang 1
Affiliation  

To investigate the incidence of postoperative deep venous thrombosis (DVP) in patients undergoing surgeries for ankle fractures and identify the associated risk factors. This was a retrospective study. A total of 1451 patients undergoing surgery of ankle fractures from January 2016 to June 2019 were included. The inpatient medical record system was inquired for data collection, including demographics, comorbidities, injury, and surgery-related data, and laboratory biomarkers. DVT of the lower extremity was diagnosed by routine Doppler examination. Univariate analyses and multivariate logistic regression analyses were used to identify the independent risk factors. Among the 1451 patients, DVT was confirmed in 38 cases, indicating an incidence of 2.6%. DVT involved both the operated and non-operated limbs in 8 patients (21.1%). DVT involved superficial femoral vein in 4 cases (6.6%), deep femoral vein in 2 (3.3%), popliteal vein in 5 (8.2%), posterior tibial vein in 11 (18.0%), and peroneal vein in 39 (63.9%). The median interval between operation and diagnosis of DVT was 7 days. Six risk factors were identified to be independently associated with DVT, including age (10-year increase) (OR, 1.44), preoperative stay (delay of each day) (OR, 1.11), anesthesia (general vs regional) (OR, 3.51), lower hemoglobin level (OR, 2.02), total cholesterol > 5.2 mmol/L (OR, 3.20), and reduced lymphocyte count (OR, 3.16). These identified factors, although not easily modifiable, do help counsel patients about the risk of DVT and help individualized assessment of the risk factors and accordingly the risk stratification.

中文翻译:

进行踝部骨折手术的患者下肢深静脉血栓形成(DVT)的发生率。

目的调查踝关节骨折手术患者术后深静脉血栓形成(DVP)的发生率,并确定相关的危险因素。这是一项回顾性研究。从2016年1月至2019年6月,共计1451例接受了踝部骨折手术的患者。查询住院病历系统以收集数据,包括人口统计学,合并症,伤害和与手术有关的数据,以及实验室生物标志物。下肢DVT通过常规多普勒检查诊断。使用单因素分析和多元逻辑回归分析来确定独立的危险因素。在1451例患者中,确诊为DVT的有38例,表明发生率为2.6%。DVT涉及8例(21.1%)的手术和非手术肢体。DVT累及股浅静脉4例(6.6%),股深静脉2例(3.3%),pop静脉5例(8.2%),胫骨后静脉11例(18.0%),腓骨静脉39例(63.9%) )。手术至诊断为DVT的中位间隔为7天。六个危险因素被确定与DVT独立相关,包括年龄(增加10年)(OR,1.44),术前住院(每天延迟)(OR,1.11),麻醉(全身与区域性)(OR,3.51) ),较低的血红蛋白水平(OR,2.02),总胆固醇> 5.2 mmol / L(OR,3.20)和减少的淋巴细胞计数(OR,3.16)。这些确定的因素尽管不容易修改,但确实可以帮助患者就DVT的风险提供咨询,并有助于对风险因素以及风险分层进行个性化评估。lite静脉5例(8.2%),胫骨后静脉11例(18.0%),腓骨静脉39例(63.9%)。手术至诊断为DVT的中位间隔为7天。六个危险因素被确定与DVT独立相关,包括年龄(增加10年)(OR,1.44),术前住院(每天延迟)(OR,1.11),麻醉(全身与区域性)(OR,3.51) ),较低的血红蛋白水平(OR,2.02),总胆固醇> 5.2 mmol / L(OR,3.20)和减少的淋巴细胞计数(OR,3.16)。这些确定的因素尽管不容易修改,但确实可以帮助患者就DVT的风险提供咨询,并有助于对风险因素以及风险分层进行个性化评估。lite静脉5例(8.2%),胫骨后静脉11例(18.0%),腓骨静脉39例(63.9%)。手术至诊断为DVT的中位间隔为7天。已确定六个与DVT独立相关的危险因素,包括年龄(增加10年)(OR,1.44),术前住院(每天延迟)(OR,1.11),麻醉(全身与区域性)(OR,3.51) ),较低的血红蛋白水平(OR,2.02),总胆固醇> 5.2 mmol / L(OR,3.20)和减少的淋巴细胞计数(OR,3.16)。这些确定的因素尽管不容易修改,但确实可以帮助患者就DVT的风险提供咨询,并有助于对风险因素以及风险分层进行个性化评估。手术至诊断为DVT的中位间隔为7天。六个危险因素被确定与DVT独立相关,包括年龄(增加10年)(OR,1.44),术前住院(每天延迟)(OR,1.11),麻醉(全身与区域性)(OR,3.51) ),较低的血红蛋白水平(OR,2.02),总胆固醇> 5.2 mmol / L(OR,3.20)和减少的淋巴细胞计数(OR,3.16)。这些确定的因素尽管不容易修改,但确实可以帮助患者就DVT的风险提供咨询,并有助于对风险因素以及风险分层进行个性化评估。手术至诊断为DVT的中位间隔为7天。六个危险因素被确定与DVT独立相关,包括年龄(增加10年)(OR,1.44),术前住院(每天延迟)(OR,1.11),麻醉(全身与区域性)(OR,3.51) ),较低的血红蛋白水平(OR,2.02),总胆固醇> 5.2 mmol / L(OR,3.20)和减少的淋巴细胞计数(OR,3.16)。这些确定的因素尽管不容易修改,但确实可以帮助患者就DVT的风险提供咨询,并有助于对风险因素以及风险分层进行个性化评估。降低血红蛋白水平(OR,2.02),总胆固醇> 5.2 mmol / L(OR,3.20)和减少淋巴细胞计数(OR,3.16)。这些确定的因素尽管不容易修改,但确实可以帮助患者就DVT的风险提供咨询,并有助于对风险因素以及风险分层进行个性化评估。降低血红蛋白水平(OR,2.02),总胆固醇> 5.2 mmol / L(OR,3.20)和减少淋巴细胞计数(OR,3.16)。这些确定的因素尽管不容易修改,但确实可以帮助患者就DVT的风险提供咨询,并有助于对风险因素以及风险分层进行个性化评估。
更新日期:2020-07-31
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